Pediatric Infectious Diseases: Open Access

Abstract

Obesity has become a rapidly growing epidemic in both adults and children. The obesity occurs due to the increased mass of adipose tissue that secrets cytokines like interleukin 6 and production of Tumor Necrotic Factor-α (TNF-α), and the condition in associated with insulin resistance. Objective: To determine the insulin resistance state and interleukin 6 levels in the serum of obese Kuwait adolescents 13-18 years, and also investigate if there is significant association between interleukin 6 and insulin resistance. Methods: The study in cross-sectional study conducted from March 2015 to June 2015 in Kuwait. Obese children were selected randomly in Farwnaiyah Primary health care center and was named the study group compared with 42 adolescents with normal Body Mass Index (BMI) i.e. the control group. The adolescents age 13-18 years, where specimens for fasting blood glucose, fasting insulin levels, Tumor Necrotic Factor-α (TNF-α), Interleukin 6 levels were estimated by Enzyme.