Respiratory Viral Detection in the Pediatric Hematopoietic Stem Cell Transplant Population

Respiratory viral infections (RVI) are a frequent cause of morbidity and mortality in hematopoietic stem cell transplant (HSCT) patients. We examined clinical characteristics and respiratory viral detection in asymptomatic pediatric HSCT pre-transplant patients and symptomatic post-transplant patients. Coxsackie/echovirus (most common virus detected pre and post-transplant), rhinovirus, and coronavirus were detected pre-transplant and at the first post-transplant event suggesting persistent detection. None of the clinical characteristics examined were associated with viral detection and there was no increase in mortality noted with asymptomatic viral detection.


David Shapiro, Maria Lopez-Marti , Christopher W Woods, Bradly P Nicholson, Paul L Martin,
Lawrence P Park, Nancy Henshaw, Andre Stokhuyzen, Rebecca Chancey and Coleen K

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